Antitumor effect
Model:
In rats Sprague against Walker 256 intramuscular  tumor system (5WA16)
in vivo


Result, opinion:
The chloroform extract of Alnus oregona has antitumor activity against Walker 256 (5WA16) tumor system. Two components of the extract that are responsible for this activity have been identified - lupeol and betulin.


Source:
Antitumor substances from Oregon alder (Alnus Oregona) [ birch family (betulaceae)].
К.Sheth, Е.Bianchi, R.Wiedhopf and J.R.Cole
National Institutes of Health, Bethesda, MD 20014, 1972



Model:
Activity against human nasopharyngeal epidermoid carcinoma in vitro

Result, opinion:
Antitumor activity of chloroform and aqueous extracts from the roots of Sarracenia flava against human epidermoid carcinomas of the nasopharynx (KB) was identified. It was found that one of the components that determine the antitumor activity is betulin. The results of studies relating to betulinic acid and its derivatives are demonstrated.



Source:
Inhibitors of tumor I: Preliminary Study of antitumor activity of Sarrazin yellow (Sarracenia flava)
D.Howard Miles, Udom Kokpol, Leon H.Zalkow, Steven J.Stewdel, and James B.Nabors

National Cancer Institute, National Institutes of Health, Bethesda, MD 20014, 1973

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